FDA/CFSAN Fish and Fisheries Products Hazards & Controls Guidance: 3rd Ed., Chapter 8

U.S. Food & Drug Administration
Center for Food Safety & Applied Nutrition
FISH AND FISHERIES PRODUCTS
HAZARDS AND CONTROLS GUIDANCE:
Third Edition June 2001

CHAPTER 8 Other Decomposition-Related Hazards
(A Chemical Hazard)

(Return to table of contents.)

Chapter 7 covers scombrotoxic poisonings in certain species of fish. These poisonings occur as a result of the formation of high levels of histamine during decomposition of the fish at improper holding temperatures.

There are indications that decomposition can result in the production of other toxins (e.g. biogenic amines, such as putrescine and cadaverine) that have the potential to cause illness, even in the absence of histamine formation. Such illnesses have been reported in a number of fish species. FDA has also received a number of consumer complaints concerning illnesses that are associated with the consumption of decomposed shrimp.

The agency intends to further evaluate the relationship between decomposition and illness. Guidance will be issued when the causes of these health effects are better understood and appropriate control measures can be recommended.

In the meantime, FDA requests that interested parties with information on this potential hazard supply any available data to the agency.

CHAPTER 8

Other Decomposition-Related Hazards (A Chemical Hazard)

Other Decomposition-Related Hazards
(A Chemical Hazard)